Rapid Separation of Enantiomeric Impurities in Chiral Molecules by a Self-Referential Weak Measurement System
نویسندگان
چکیده
منابع مشابه
Enantiomeric Separation of Rivaroxaban by a Chiral Liquid Chromatographic Method
Methods: An enantioselective reversed phase high performance liquid chromatographic method was developed and validated. The enantiomers of rivaroxaban was resolved on a Chiralcel OD-H (250 mm × 4.6 mm, 5 mm) column using a mobile phase system containing n-hexane –isopropanol (50: 50 v/v/) and column temperature at 35°C. The resolution between the enantiomers was not less than 2.0. The developed...
متن کاملEnantiomeric separation of Linezolid by chiral reversed-phase liquid chromatography.
A chiral liquid chromatographic method is developed for the enantiomeric resolution of Linezolid, (S)(-)-N-[[-3-(3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl] methyl] acetamide, an antibiotic in bulk drugs. The enantiomers of Linezolid are resolved on a Chiralcel OJ-RH column using a mobile phase system containing 150mM di-sodium hydrogen phosphate buffer (pH 4.5)-acetonitrile (86:14,...
متن کاملWeak Force Measurement in Bistable Optomechanical System
One of the main milestones in the study of opto-mechanical system is to increase the sensitivity of weak forces measurement up to the standard quantum limit. We have studied the detection of weak force under a bistable condition in red detuned regime. In this case, dynamics of the system behaves asymptotically similar to stationary state and applying external force affects phase and fluctuation...
متن کاملA numerical renormalization group approach for calculating the spectrum of a vibronic system occurring in molecules or impurities in insulators
Theoretically, in order to describe the behavior of a spectrum, a mathematical model whichcould predict the spectrum characteristics is needed. Since in this study a Two-state system has beenused like models which was introduced previously past and could couple with the environment, theformer ideas have been extended in this study. we use the second quantized version for writing thisHamiltonian...
متن کاملChiral Separation in Preparative Scale: A Brief Overview of Membranes as Tools for Enantiomeric Separation
Given the importance of chirality in the biological response, regulators, industries and researchers require chiral compounds in their enantiomeric pure form. Therefore, the approach to separate enantiomers in preparative scale needs to be fast, easy to operate, low cost and allow obtaining the enantiomers at high level of optical purity. A variety of methodologies to separate enantiomers in pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Sensors
سال: 2018
ISSN: 1424-8220
DOI: 10.3390/s18113788